Evaluation of Diagnostics Colistin MIC-Strip Test for Colistin Susceptibility Testing

Colistin Susceptibility Testing Using the MicroScan® Colistin Well

Colistin susceptibility testing: time for a review.

respectively, relative to the S. maltophilia strain IAM 1566 protein) (Figure 1). S. maltophilia is a Gram-negative bacterium found in a variety of environments, including soil, water and plants, and is therefore a potential reservoir of the MBL gene. Similar to POM-1 and L1 MBLs, the ability of the PAM-1 enzyme to hydrolyse carbapenems might be relatively low; consequently, the PAM-1-positive ...

Evaluation of MIC Strip Isavuconazole Test for Susceptibility Testing of Wild-Type and Non-Wild-Type Aspergillus fumigatus Isolates

We evaluated the MIC Strip Isavuconazole test against EUCAST E.Def 9.3 by using 40 wild-type and 39 CYP51A mutant Aspergillus fumigatus strains. The strip full inhibition endpoint (FIE) and 80% growth inhibition endpoint were determined by two independent readers, reader 1 (R1) and R2. The essential (within ±0, ±1, and ±2 twofold dilutions) and categorical agreements were best with the FIE (for...

Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate.

OBJECTIVES To determine the disposition of colistin methanesulphonate (CMS) and colistin following intravenous (iv) administration of CMS in rats. METHODS Five rats received a single iv bolus of 15 mg/kg CMS. Plasma concentrations of CMS and of colistin formed by the hydrolysis of CMS were determined by HPLC. The pharmacokinetic parameters of CMS and colistin were calculated using non-compart...

Colistin Susceptibility Testing of Enterobacteriaceae by Agar Dilution (AD), Broth Microdilution (BMD) and Polymyxin NP

2033. Evaluation of the FilmArray Meningitis/Encephalitis Molecular Panel in a Tertiary Care Public County Hospital Tae Hun Kim, MD; Emi Minejima, PharmD; Brad Spellberg, MD; Ira Shulman, MD; Paul Holtom, MD; Tarina Kang, MD and Susan M. Butler-Wu, PhD; Pathology, LAC-USC Medical Center, Los Angeles, California, Pharmacy, USC School of Pharmacy, Los Angeles, California, LAC-USC Medical Center, ...